ENGLISH MAGAZINE
Exhaustion TEXture: metabolism and epigenetic meet on the core for CART-driven opportunities
Persistent antigen stimulation, as observed in cancer and chronic infections, leads to T cell exhaustion (TEX), a state of impaired effector functions. Typically, TEX has been...
ENGLISH MAGAZINE
Brain cancer “going APE”: here is its way to resist TMZ and leave DNA repair BEReft with options
In spite of intensive research, glioblastoma remains one of the most lethal types of brain cancer. Despite there are several available medications, temozolomide (TMZ) is...
ENGLISH MAGAZINE
“Spark the feed”: GLP-1 is not the only one to regulate energy, since the Arc reactor needs TRH and GABA to process
Obesity stands as one major global health issue, with limited effective and sustainable treatment options. Lately-introduced GLP-1 receptor agonists, which have been widely used...
ENGLISH MAGAZINE
Systemic mastocytosis under siege: release the new weapon first, then “do the math” to estimate efficacy
Systemic mastocytosis (SIM) is characterized by an abnormal accumulation of mast cells, a type of immune cell present throughout the body that contributes to...
ENGLISH MAGAZINE
Autoimmunities after infertility? A representative population with its prevalence, risks and possible mechanisms
Women who experience infertility but do not use fertility treatments have a higher risk of developing a group of conditions called systemic autoimmune rheumatic...
ENGLISH MAGAZINE
The responses of the several breast cancer subtypes to steroid hormones: a brief-indepth biology look
Sex hormones are an important part of both the pathogenesis and progression of breast cancer. Each of them has its own molecular actions on...
ENGLISH MAGAZINE
“Lend me your proteins to keep the balance”: here’s the shadowy, helpful role of platelets in immunity
Monocytes, a special type of white blood cell, secrete cytokines as inflammatory messengers that are crucial for an adequate immune response. Monocytes are white...
ENGLISH MAGAZINE
High cholesterol in youth: a risk factor for atherosclerosis in the adult age
Atherosclerosis is a major cause of cardiovascular diseases, including heart attack and stroke. Traditionally, risk factors for atherosclerosis, such as high blood pressure, obesity,...